Compact Granulation System CGS

The Diosna CGS (Compact Granulation System) is state of the art granulation production in the world's most compact, flexible and integrated plant.

The CGS system is engineered from the ground up to optimize yield and operator ergonomics. The results are very impressive and have given the Pharmaceutical Industry a new leading standard in excellence of design.

The CGS system design advantage is in close coupling technology developed by Diosna, which reduces the transfer distances between all processes while optimizing each of those processes though various techniques. The results speak for themselves: higher product yields, easiest access for inspection and cleaning, smallest installation in process room, improved GMPs throughout process train and simplified process. Validation though one highly integrated 21 CFR Part 11 control system.

Processes offered:

• Dry mixing/wet granulating/hot melt granulating/vacuum drying (with gas stripping aka "one pot processing"), 
• Wet calibrating of product (milling) using quadro comil or similar conical screen mill, 
• Fluid bed drying/top spray granulating/bottom or tangential spray granulating / wurster coating, 
• Dry milling (employing whatever mill is required by your process, generally quadro comil is used), 
• Bin blending/drum blending /v-blending with optional integrated weighing system in blender (no floor scale required), 
• High containment to ~400 nano-gram (ETWA) throughout system from initial loading of granulator to final transfer to bin/drum/v-shell.