Closed Combined Granulation System 150 - 1300

Diosna machines and equipment are used by leading companies worldwide. They are the product of proven reliability and know-how in a wide variety of applications and handling many products.

Diosna Systems stand for innovative pharmaceutical production equipment of constantly high quality. Diosna offers the principal elements of modern solids production plant - the mixer-granulator and fluid bed dryer - from one source. In our CCS concept these two pieces of equipment are coupled together. This allows optimal arrangement of the production area, and the most effective interfacing.

Mixers and dryers are matched. The installation can be optimised, and maximum efficiency of the production process is guaranteed. Either vertical or horizontal product flow can be provided. Both pieces of equipment are operated from a common operator interface. Nevertheless each machine remains independent and can be run without the other at any time. Not only does the combination of the items of plant allow completely closed product transfer and the utilization of common cleaning devices but also gives simple and effective controls for the operating and maintenance personnel.

Closed Combined System CCS 150 - 1300 at a glance.

• Efficiency: reproducible processes and automated programmes with low set-up times,
• Safety: individual consideration to ATEX norms of all explosion risks,
• Through-the-wall-concept: strict separation of production and technical areaContainment conscious design: processing of the product in a closed system, special solutions for highly active substances,
• From one source: complete range of equipment for materials handling and product preparation,
• Future-proof: Top-Spray-/ Bottom-Spray-processes in the fluid bed dryer,
• Qualification: Pharmaceutical industry qualification standards to GAMP 4.

Mixing, granulation and drying in combination. Diosna provides the core elements of a modern solid dose manufacturing facility from a single source: the mixer-granulator and the fluidized bed dryer. The two systems are connected in DIOSNA CCS concept directly. Thus they can be ideally fit into the production area. Mixers and dryers are ideally matched. Thus, the planned installation and ensuring maximum efficiency of the production process are saved. The product flow can be realized alternatively vertically or horizontally.